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Using two separate drugs to shed weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you need to err assisting caution and allow the FDA do its job and demand some study be done so that the public is aware of the side effects and hazards of the medications before we drive them. Keep in mind that drug companies come in business to earn money and that they would say anything to keep people on the medications. Researchers discovered that participants investing in this drug for the year, dropped excess weight within four weeks and have kept the weight off through the 56 weeks of the study. Contrave is often a combination of the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which can be made up of more than one active ingredient, which might make them more effective and safer. Combo-pilling will be the newest fad or also the newest to come under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills has become popular could be the fact that at the time of right now there are not any long term prescription weight loss supplements that have been approved by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug may also raise blood pressure levels and pulse rate, and must not be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure and pulse rate and must stop used in patients with uncontrolled high blood pressure levels, along with by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients on the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking. From a psychiatric standpoint, evidence implies that the ordinary neural mechanism for goal-directed behavior may be hijacked from the addiction, and malfunctions in such a way that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus along with the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).