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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantage of the drug outweighs the risk of a possible increase in blood pressure. Using two separate drugs to lose weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people that go through it one should err assisting caution and permit the FDA do its job and demand some investigation be done so that the public understands the side effects and hazards of the medications before we take them. Keep in mind that drug companies come in business to generate money and that they would say anything to keep people on their medications. Researchers found that participants using this drug for any year, dropped a few pounds within a month and have kept the load off during the entire 56 weeks from the study. Contrave is really a combination in the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of many active ingredient, which can make them more effective and safer. Combo-pilling is the newest fad or in addition to this the newest in the future under scrutiny and thus it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills has become popular will be the fact that since right now there aren't long term prescription weight loss supplements that have been approved by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and mustn't be taken in people with seizure disorders. The drug also can raise hypertension and heart rate, and really should not be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and heart rate and must not used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. An independent report published by Gant Daily in April also stated that naltrexone also works well with kleptomaniacs and gambling addicts, at the same time. Citing research in the University of Minnesota School of Medicine, Gant Daily reported the drug creates kleptomaniacs and chronic gamblers in the same way with alcohol and opioid addicts'by blocking the end results of endorphins, that this brain releases when experiencing craving or compulsions.