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Using two separate drugs to shed pounds can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you should err on the side of caution and permit the FDA do its job and demand some investigation be done so that the public is aware of the side effects and risks of the medications before we take them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on the medications. Researchers discovered that participants taking this drug for the year, dropped a few pounds within four weeks and have kept the body weight off during the entire 56 weeks in the study. Contrave can be a combination of the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which might be made up of several active ingredient, which may make them more efficient and safer. Combo-pilling is the newest fad or also the newest ahead under scrutiny and therefore it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills has become popular may be the fact that as of right now there aren't any long term prescription weight loss supplements that have been licensed by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise hypertension and pulse rate, and really should not be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must stop used in patients with uncontrolled high blood pressure, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients on the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking. Other people who should not use Contrave are patients being affected by bulimia, anorexia nervosa, anyone using opiods, and patients undergoing an 'abrupt discontinuation of alcohol, benzodiazepines, barbiturates and antiepileptic drugs.' Lastly Concave should not be prescribed for ladies who are pregnant or trying to become pregnant.