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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantages of the drug outweighs the risk of a possible surge in blood pressure. Using two separate drugs to lose weight naturally can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it one should err on the side of caution and let the FDA do its job and demand some investigation be done so that the public understands the side effects and hazards of the medications before we bring them. Keep in mind that drug companies have been in business to make money and that they would say anything to keep people on their medications. Researchers found that participants taking this drug for a year, dropped excess weight within four weeks and have kept the load off through the 56 weeks with the study. Contrave is really a combination in the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs that are made up of more than one active ingredient, that might make them more efficient and safer. Combo-pilling is the newest fad or also the newest in the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is now popular could be the fact that since right now there aren't any long term prescription diet pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and must not be taken in people who have seizure disorders. The drug can also raise blood pressure level and heartrate, and shouldn't be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must not used in patients with uncontrolled high blood pressure levels, along with by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients for the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking. New UCLA study on smokers with mental, drug, and alcohol problems